Fenofibrate

What is the most important information I should know about Fenofibrate?

· Rarely, treatment with Fenofibrate has been associated with a serious side effect affecting the muscles. Contact your doctor immediately if you experience unusual or unexplained muscle pain, tenderness, or weakness especially if accompanied by fever or a "flulike" feeling.

· Avoid alcohol or use it only in moderation while taking Fenofibrate. Alcohol can raise triglyceride levels, and it can be damaging to the liver while you are taking Fenofibrate.

· Follow any special diet and exercise plan recommended by your doctor while taking this medication. Diet and exercise are important factors in controlling cholesterol.

 

What is Fenofibrate?

· Fenofibrate is a fibric acid derivative. Fenofibrate helps reduce types of fat in the blood. Fenofibrate is especially good at lowering triglycerides and a form of cholesterol called very-low-density lipoprotein (VLDL). High levels of these types of fat in the blood are associated with an increased chance of pancreatitis, an inflammation of the pancreas that can result in severe stomach pain and even death.

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· Fenofibrate is used to reduce triglycerides and cholesterol in the blood.

· Fenofibrate may also be used for purposes other than those listed in this medication guide.

 

What should I discuss with my healthcare provider before taking Fenofibrate?

· Before taking Fenofibrate, tell your doctor if you have     ·liver disease,     ·biliary cirrhosis,     ·kidney disease,     ·gallbladder disease,     ·hypothyroidism (an underactive thyroid gland), or     ·diabetes.

· You may not be able to take Fenofibrate, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.

· Fenofibrate is in the FDA pregnancy category C. This means that it is not known whether Fenofibrate will be harmful to an unborn baby. Do not take Fenofibrate without first talking to your doctor if you are pregnant or could become pregnant during treatment.

· Fenofibrate should not be used by nursing mothers. Do not take Fenofibrate without first talking to your doctor if you are breast-feeding a baby.

 

How should I take Fenofibrate?

· Take Fenofibrate exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.

· Take each dose with a full glass of water.

· Take Fenofibrate with a meal or with food.

· It is important to take Fenofibrate regularly to get the most benefit.

· Your doctor may want you to have blood tests or other medical evaluations during treatment with Fenofibrate to monitor progress and side effects.

· Store Fenofibrate at room temperature away from moisture and heat.

 

What happens if I miss a dose?

· Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication unless your doctor directs otherwise.

 

What happens if I overdose?

· Seek emergency medical attention if an overdose is suspected.

· Symptoms of a Fenofibrate overdose are not known.

 

What should I avoid while taking Fenofibrate?

· Follow any diet or exercise plan outlined by your doctor. Diet and exercise are important factors in controlling cholesterol.

· Avoid alcohol or use it only in moderation while taking Fenofibrate. Alcohol can raise triglyceride levels, and it can be damaging to the liver while you are taking Fenofibrate.

 

What are the possible side effects of Fenofibrate?

· Rarely, treatment with Fenofibrate has been associated with a serious side effect affecting the muscles. Contact your doctor immediately if you experience unusual or unexplained muscle pain, tenderness, or weakness especially if accompanied by fever or a "flulike" feeling.

· If you experience any of the following serious side effects, stop taking Fenofibrate and contact your doctor or seek medical attention:     ·an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);     ·severe stomach pain, nausea, or vomiting;     ·fever.

· Other, less serious side effects may be more likely to occur. Continue to take Fenofibrate and talk to your doctor if you experience     ·joint pain;     ·indigestion;     ·bloating or flatulence; or     ·a rash.

· Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

 

What other drugs will affect Fenofibrate?

· Before taking Fenofibrate, talk to your doctor if you are taking any of the following medicines:     ·an anticoagulant (blood thinner) such as warfarin (Coumadin);     ·cyclosporine (Neoral, Sandimmune);     ·lovastatin (Mevacor), simvastatin (Zocor), pravastatin (Pravachol), fluvastatin (Lescol), atorvastatin (Lipitor), or cerivastatin (Baycol); or     ·cholestyramine (Questran) or colestipol (Colestid).

· You may not be able to take Fenofibrate, or you may require a dosage adjustment or special monitoring during treatment if you are taking any of the drugs listed above.

· Drugs other than those listed here may also interact with Fenofibrate. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

 

Where can I get more information?

· Your pharmacist has additional information about Fenofibrate written for health professionals that you may read.