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Generic Name: labetalol
Brands: Normodyne, Trandate

What is the most important information I should know about Labetalol?

· Do not stop taking Labetalol without first talking to your doctor. Stopping abruptly may make your condition worse.

· Call your doctor immediately if you experience shortness of breath.

· Use caution when driving, operating machinery, or performing other hazardous activities. Labetalol may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities.


What is Labetalol?

· Labetalol is in a class of drugs called beta-blockers. Beta-blockers affect the heart and circulatory system (arteries and veins).

· Labetalol is used to treat hypertension (high blood pressure).

· Labetalol may also be used for purposes other than those listed in this medication guide.


What should I discuss with my healthcare provider before taking Labetalol?

· Before taking Labetalol, tell your doctor if you have     ·asthma;     ·a heart problem such as low blood pressure, a slow heart rate, heart block, sick sinus syndrome, a pacemaker, heart failure, and others;     ·diabetes;     ·depression;     ·thyroid disease;     ·kidney disease;     ·liver disease; or     ·any type of circulatory disease.

· You may not be able to take Labetalol, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.

· Labetalol is in the FDA pregnancy category C. This means that it is not known whether Labetalol will harm an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant or could become pregnant during treatment.

· Labetalol passes into breast milk in small amounts and may affect a nursing infant. Do not take Labetalol without first talking to your doctor if you are breast-feeding a baby.


How should I take Labetalol?

· Take Labetalol exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.


· Take each dose with a full glass of water.

· Take Labetalol with food or immediately following a meal.

· Take Labetalol at the same time every day whenever possible.

· Do not stop taking Labetalol without first talking to your doctor. Stopping abruptly may make your condition worse.

· Store this medication at room temperature away from moisture and heat.


What happens if I miss a dose?

· Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose.Do not take a double dose of this medication.


What happens if I overdose?

· Seek emergency medical attention.

· Symptoms of a Labetalol overdose include a slow heart beat, shortness of breath, fainting, dizziness, weakness, confusion, nausea, and vomiting.


What should I avoid while taking Labetalol?

· Use caution when driving, operating machinery, or performing other hazardous activities. Labetalol may cause drowsiness, dizziness, and blood pressure changes. If you experience drowsiness or dizziness, avoid these activities.

· Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking this medication.

· Tell your doctor and dentist that you are taking this medication before having surgery.


What are the possible side effects of Labetalol?

· If you experience any of the following serious side effects stop taking Labetalol and call your doctor immediately or seek emergency medical treatment:     ·an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; hives);     ·wheezing or shortness of breath;     ·an unusually slow or irregular heart beat;     ·swelling of the feet and lower legs;     ·leg pain or cramping;     ·sudden weight gain (more than 2 pounds in one day or 5 pounds in one week);     ·chest (heart) pain;     ·unusually cold or blue feet and hands; or     ·skin rash.

· If you experience any of the following less serious side effects, continue taking Labetalol and talk to your doctor:     ·fatigue or confusion;     ·headache or dizziness;     ·weak pulse or mildly slow heart rate;     ·diarrhea, constipation, gas, nausea, or vomiting;     ·depression;     ·nightmares; or     ·impotence (difficulty obtaining or maintaining an erection).

· Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.


What other drugs will affect Labetalol?

· Before taking Labetalol, tell your doctor if you are taking     ·a heart medication such as nifedipine (Procardia, Adalat), reserpine (Serpasil), verapamil (Calan, Verelan, Isoptin), diltiazem (Cardizem, Dilacor XR), clonidine (Catapres), digoxin (Lanoxin), doxazosin (Cardura), guanadrel (Hylorel), prazosin (Minipress), or terazosin (Hytrin);     ·a diabetes medication such as insulin, glyburide (Diabeta, Micronase, Glynase), glipizide (Glucotrol), chlorpropamide (Diabinese), or metformin (Glucophage);     ·a nonsteroidal anti-inflammatory drug (NSAID) such as ibuprofen (Motrin, Advil, others), naproxen (Aleve, Anaprox, Naprosyn, others), ketoprofen (Orudis, Orudis KT, Oruvail), and others;     ·a respiratory medication such as albuterol (Ventolin, Proventil, Volmax, others), bitolterol (Tornalate), metaproterenol (Alupent, Metaprel), pirbuterol (Maxair), terbutaline (Brethaire, Brethine, Bricanyl), or theophylline (Theo-Dur, Theochron, Theolair, others), and others;     ·the stomach medication cimetidine (Tagamet, Tagamet HB); or     ·prescription or over-the-counter cough medicines, cold medicines, or diet pills.

· Drugs other than those listed here may also interact with Labetalol or affect your condition. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including herbal products.


Where can I get more information?

· Your pharmacist has additional information about Labetalol written for health professionals that you may read.

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