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Secobarbital

Generic Name: secobarbital
Brands: Seconal Sodium


What is the most important information I should know about Secobarbital?

· Call your doctor immediately if you develop a fever, a sore throat, sores in your mouth, broken blood vessels under your skin, or easy bruising or bleeding. These could be early signs of a serious side effect.

· Use caution when driving, operating machinery, or performing other hazardous activities. Secobarbital will cause drowsiness. If you experience drowsiness, avoid these activities.

· Do not drink alcohol or take other sleep medicines, antihistamines, narcotic pain relievers, or other drugs that also cause drowsiness unless your doctor approves. Dangerous sedation could result.

· Secobarbital may decrease the effectiveness of birth control pills. Use a second method of birth control while taking Secobarbital to prevent pregnancy.

 

What is Secobarbital?

· Secobarbital is in a class of drugs called barbiturates (bar bi TURE ates). Secobarbital depresses the activity of your brain and nervous system.

· Secobarbital is used to treat insomnia (for up to 2 weeks). After 2 weeks, this medication appears to lose its effectiveness.

· The injectable form of Secobarbital is also used induce sleep, especially before surgery.

· Secobarbital may also be used for purposes other than those listed in this medication guide.

 

Who should not take Secobarbital?

· Do not take Secobarbital if you have     ·porphyria,     ·liver disease,     ·kidney disease, or     ·severe respiratory disease such as severe asthma or severe chronic obstructive pulmonary disorder (COPD).

· Before taking this medication, tell your doctor if you have ever had a drug or alcohol addiction in the past. Secobarbital is habit forming, which means that you can become addicted to it.

· Secobarbital is in the FDA pregnancy category D. This means that it is known to harm an unborn baby. Do not take Secobarbital if you are pregnant.

· Secobarbital passes into breast milk and could affect a nursing infant. Do not take Secobarbital without first talking to your doctor if you are breast-feeding a baby.

 

· Secobarbital may cause excitement, irritability, aggression, depression, or confusion-- particularly in children and in adults over 60 years of age. Lower doses and close monitoring may be necessary.

 

How should I take Secobarbital?

· Take Secobarbital exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

· Take each dose with a full glass of water.

· To treat insomnia, Secobarbital is usually taken just before bedtime. Take your dose when you are ready to get into bed, or not long before, so that if you become sleepy, you will not fall or become confused and accidentally injure yourself. Secobarbital should not be used for longer than 2 weeks to treat insomnia.

· Do not increase your dosage of this medicine without the approval of your doctor. If your symptoms are not being adequately treated, talk to your doctor.

· Store Secobarbital at room temperature away from moisture and heat.

 

What happens if I miss a dose?

· Since Secobarbital is usually taken as needed to treat insomnia, missing a dose is usually not a problem. Take the missed dose as soon as you remember if it is needed. Do not take a double dose of this medication.

 

What happens if I overdose?

· Seek emergency medical attention.

· Symptoms of a Secobarbital overdose include difficulty breathing, back-and-forth movements of the eyes, appearance of being drunk, fast heartbeat, low body temperature, heavy sedation, coma, and death.

 

What should I avoid while taking Secobarbital?

· Use caution when driving, operating machinery, or performing other hazardous activities. Secobarbital will cause drowsiness. If you experience drowsiness, avoid these activities.

· Do not drink alcohol or take other sleep medicines, antihistamines, narcotic pain relievers, or other medicines that cause drowsiness unless your doctor approves. Dangerous sedation could result.

· Do not increase your dosage of this medicine without the approval of your doctor. If your symptoms are not being adequately treated, talk to your doctor.

· Do not take this medicine for longer than 2 weeks to treat insomnia.

· Secobarbital may decrease the effectiveness of birth control pills. Use a second method of birth control while taking Secobarbital to prevent pregnancy.

 

What are the possible side effects of Secobarbital?

· If you experience any of the following serious side effects, stop taking Secobarbital and seek emergency medical attention or call your doctor immediately:     ·an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);     ·a fever or a sore throat;     ·sores in your mouth;     ·broken blood vessels under your skin; or     ·easy bruising or bleeding.

· Other, less serious side effects may be more likely to occur. Continue to take Secobarbital and talk to your doctor if you experience     ·drowsiness or dizziness;     ·confusion;     ·agitation, irritability, or excitability;     ·nightmares, nervousness, or anxiety;     ·headache; or     ·"hangover" effect (drowsiness the day after a dose).

· Secobarbital is habit forming, which means that you can become addicted to it. Your doctor will want to monitor how much medicine you are taking. Your dosage may have to be reduced slowly to prevent withdrawal effects.

· Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

 

What other drugs will affect Secobarbital?

· Large chronic doses of Secobarbital may cause liver damage if it is taken with acetaminophen (Tylenol, others). Tell your doctor and pharmacist if you are taking Secobarbital on a regular basis. Pain and fever reducers other than acetaminophen are available and may be more suitable choices.

· Secobarbital may decrease the effectiveness of many drugs, including the following:     ·blood thinners such as warfarin (Coumadin). Blood clotting could result.     ·carbamazepine (Tegretol) and clonazepam (Klonopin). Reduced effectiveness of these medicines could lead to poor seizure control.     ·birth control pills. Breakthrough bleeding or unplanned pregnancy could result. Use of a second form of birth control is recommended.     ·steroid medicines such as hydrocortisone (Cortef, Hydrocortone), prednisone (Orasone, Deltasone), prednisolone (Prelone, Delta Cortef), methylprednisolone (Medrol), and others.     ·felodipine (Plendil), verapamil (Calan, Verelan, Isoptin), and quinidine (Cardioquin, Quinidex, Quinora, Quinaglute). Reduced effectiveness could lead to poor control of blood pressure, irregular heartbeats, or other heart conditions.     ·fenoprofen (Nalfon). Reduced effectiveness could lead to a loss of inflammation or pain control.     ·griseofulvin (Grisactin, Fulvicin PG, Grifulvin V), and metronidazole (Flagyl, Metryl, Metizol). Reduced effectiveness could lead to recurrence or worsening of an infection.     ·theophylline (Theo-Dur, Theochron, Theolair, Slo-Bid, others). Asthma, COPD, or other respiratory conditions could grow worse.

· Other drugs may also influence the activity of Secobarbital:     ·Alcohol, sleep aids, antihistamines, antidepressants, and other drugs that cause tiredness or sedation may increase the drowsiness caused by Secobarbital.     ·Rifampin (Rifadin, Rimactine) may decrease the effects of Secobarbital.

· Drugs other than those listed here may also interact with Secobarbital. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

 

Where can I get more information?

· Your pharmacist has more information about Secobarbital written for health professionals that you may read.


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