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Serentil

Generic Name: mesoridazine
Brands: Serentil


What is the most important information I should know about Serentil?

· In rare cases, Serentil has caused serious irregular heartbeats, sometimes resulting in death. Do not take Serentil if you have any of the following conditions or a history of these conditions: heart disease; an irregular heartbeat or a history of irregular heartbeats; a history of prolonged QT intervals; a family history of congenital long QT syndrome; hypokalemia (low levels of potassium in your blood); slow heartbeats that require treatment; or other heartbeat disturbances. These conditions may increase the risk of irregular heartbeats, heart attack, and death while taking Serentil.

· Do not take Serentil with other drugs that can affect heartbeat rhythms such as quinidine (Cardioquin, Quinaglute, Quinidex, others), procainamide (Procan, Procanbid, Pronestyl), disopyramide (Norpace), and others. Taken with any of these drugs, Serentil (Serentil) may cause irregular heartbeats that could lead to death. This is not a complete list of drugs that may interact with Serentil and cause heart problems. Talk to your doctor or pharmacist before taking any other prescription or over-the-counter medications.

· Call your doctor immediately if you have uncontrollable movements of the mouth, tongue, cheeks, jaw, arms, or legs; fever; muscle rigidity; sweating; irregular pulse; or fast or irregular heartbeats.

· Use caution when driving, operating machinery, or performing other hazardous activities. Serentil may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities.

· Dizziness may be more likely to occur when you rise from a sitting or lying position. Rise slowly to prevent dizziness and a possible fall.

· Serentil may interact with other drugs that cause drowsiness, including alcohol, antidepressants, antihistamines, pain relievers, anxiety medicines, seizure medicines, and muscle relaxants. Dangerous sedation, dizziness, or drowsiness may occur if Serentil is taken with alcohol or any of these medications. Talk to your doctor before taking Serentil in combination with alcohol or any other prescription or over-the-counter medicines.

· Do not mix the liquid form of this medication with coffee, cola, or tea.

 

What is Serentil?

· Serentil is in a class of drugs called phenothiazines. It works by changing the actions of chemicals in your brain.

· Serentil is used to treat schizophrenia.

· Serentil may also be used for purposes other than those listed in this medication guide.

 

Who should not take Serentil?

· In rare cases, Serentil has caused serious irregular heartbeats, sometimes resulting in death. Do not take Serentil if you have any of the following conditions or a history of these conditions: heart disease; an irregular heartbeat or a history of irregular heartbeats; a history of prolonged QT intervals; a family history of congenital long QT syndrome; hypokalemia (low levels of potassium in your blood); slow heartbeats that require treatment; or other heartbeat disturbances. These conditions may increase the risk of irregular heartbeats, heart attack, and death while taking Serentil.

· Before taking this medication, tell your doctor if you have     ·a bone marrow disease,     ·glaucoma,     ·seizures,     ·Parkinson's disease,     ·an enlarged prostate or difficulty urinating,     ·liver disease, or     ·kidney disease.

 

· You may not be able to take Serentil, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.

· It is not known whether Serentil will harm an unborn baby. Do not take Serentil without first talking to your doctor if you are pregnant.

· It is not known whether Serentil passes into breast milk. Do not take Serentil without first talking to your doctor if you are breast-feeding a baby.

· If you are over 60 years of age, you may be more likely to experience side effects from Serentil. You may require a lower dose of this medication.

 

How should I take Serentil?

· Take Serentil exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.

· Take each dose with a full glass (8 ounces) of water.

· Serentil can be taken with or without food or milk.

· Mix the concentrate with 2 to 4 ounces of water, noncola soda, juice, milk, or semisolid food such as applesauce or pudding.

· Do not mix the liquid with coffee, tea, or cola.

· Do not let the liquid touch your skin or clothes.

· Do not stop taking Serentil without first talking to your doctor. It may be several weeks before you begin to feel better, and you may require continuous treatment for quite some time.

· Throw away any discolored liquid.

· Store Serentil at room temperature away from moisture and heat. Store the liquid in a light-resistant container.

 

What happens if I miss a dose?

· Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the dose you missed and take only your next regularly scheduled dose. Do not take a double dose of this medication.

 

What happens if I overdose?

· Seek emergency medical attention.

· Symptoms of a Serentil overdose include uncontrollable movements, agitation, seizures, severe dizziness or fainting, coma, very deep sleep, irregular heartbeats, and high or low body temperature.

 

What should I avoid while taking Serentil?

· Use caution when driving, operating machinery, or performing other hazardous activities. Serentil may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities.

· Dizziness may be more likely to occur when you rise from a sitting or lying position. Rise slowly to prevent dizziness and a possible fall.

· Serentil may interact with other drugs that cause drowsiness, including alcohol, antidepressants, antihistamines, pain relievers, anxiety medicines, seizure medicines, and muscle relaxants. Dangerous sedation, dizziness, or drowsiness may occur if Serentil is taken with alcohol or any of these medications. Talk to your doctor before taking Serentil in combination with alcohol or any other prescription or over-the-counter medicines.

· Avoid prolonged exposure to sunlight. Serentil may increase the sensitivity of your skin to sunlight. Use a sunscreen and wear protective clothing when sun exposure is unavoidable.

 

What are the possible side effects of Serentil?

· If you experience any of the following serious side effects, stop taking Serentil and seek emergency medical treatment:     ·an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);     ·uncontrollable movements of the mouth, tongue, cheeks, jaw, arms, or legs;     ·fever;     ·muscle rigidity;     ·muscle spasms of the face or neck;     ·sweating;     ·irregular pulse;     ·fast or irregular heartbeats.     ·severe restlessness or tremor;     ·severe drowsiness;     ·blurred vision;     ·dizziness or fainting; or     ·a rash.

· Other, less serious side effects may be more likely to occur. Continue to take Serentil and talk to your doctor if you experience:     ·dry mouth or stuffy nose;     ·constipation;     ·mild restlessness, drowsiness, or tremor;     ·difficult urination or dark urine;     ·decreased sex drive;     ·increased appetite; or     ·menstrual irregularities or swollen breasts.

· Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

 

What other drugs will affect Serentil?

· Do not take Serentil with other drugs that can affect heartbeat rhythms such as quinidine (Cardioquin, Quinaglute, Quinidex, others), procainamide (Procan, Procanbid, Pronestyl), disopyramide (Norpace), and others. Taken with any of these drugs, Serentil (Serentil) may cause irregular heartbeats that could lead to death. This is not a complete list of drugs that may interact with Serentil and cause heart problems. Talk to your doctor or pharmacist before taking any other prescription or over-the-counter medications.

· Serentil may interact with other drugs that cause drowsiness, including alcohol, antidepressants, antihistamines, pain relievers, anxiety medicines, seizure medicines, and muscle relaxants. Dangerous sedation, dizziness, or drowsiness may occur if Serentil is taken with alcohol or any of these medications. Talk to your doctor before taking Serentil in combination with alcohol or any other prescription or over-the-counter medicines.

· Drugs other than those listed here may also interact with Serentil. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

 

Where can I get more information?

· Your pharmacist has additional information about Serentil written for health professionals that you may read.


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