Thorazine

What is the most important information I should know about Thorazine?

· Call your doctor immediately if you have uncontrollable movements of the mouth, tongue, cheeks, jaw, arms, or legs.

· Use caution when driving, operating machinery, or performing other hazardous activities. Thorazine may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities.

· Dizziness may be more likely to occur when you rise from a sitting or lying position. Rise slowly to prevent dizziness and a possible fall.

· Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking Thorazine.

· Do not crush or chew the sustained-release formulations of Thorazine. Swallow them whole. They are specially formulated to release slowly in your body. If you do not know if your medication is a sustained-release formulation, ask your pharmacist.

 

What is Thorazine?

· Thorazine is in a class of drugs called phenothiazines. It works by changing the actions of chemicals in your brain.

· Thorazine is used to treat psychotic disorders, nausea and vomiting, chronic hiccups, and acute intermittent porphyria.

· Thorazine may also be used for purposes other than those listed in this medication guide.

 

Who should not take Thorazine?

· Before taking this medication, tell your doctor if you have     ·a bone marrow disease,     ·glaucoma,     ·seizures,     ·Parkinson's disease,     ·an enlarged prostate or difficulty urinating,     ·liver disease, or     ·kidney disease.

· You may not be able to take Thorazine, or you may require a lower dose or special monitoring if you have any of the conditions listed above.

· It is not known whether Thorazine will harm an unborn baby. Do not take Thorazine without first talking to your doctor if you are pregnant.

· Thorazine passes into breast milk and may affect a nursing baby. Do not take Thorazine without first talking to your doctor if you are breast-feeding a baby.

· If you are over 60 years of age, you may be more likely to experience side effects from Thorazine. You may require a lower dose of this medication.

 

How should I take Thorazine?

· Take Thorazine exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.

· Take each dose with a full glass (8 ounces) of water.

· Thorazine can be taken with or without food or milk.

· Do not crush or chew the sustained-release formulations of Thorazine. Swallow them whole. They are specially formulated to release slowly in your body. If you do not know if your medication is a sustained-release formulation, ask your pharmacist.

· Mix the concentrate with 2 to 4 ounces of water, soda, juice, coffee, tea, syrup, milk, or a semisolid food such as applesauce or pudding.

· Do not stop taking Thorazine without the approval of your doctor. It may be several weeks before you begin to feel better, and you may require continuous treatment for quite some time. Talk to your doctor before you stop taking this medication.

· Throw away any discolored liquid.

· Store Thorazine at room temperature away from moisture and heat.

 

What happens if I miss a dose?

· If you take one dose of Thorazine a day, take the missed dose as soon as you remember, then go back to your regular schedule the next day. If you do not remember until it is time for your next dose, skip the dose you missed and take only your next regularly scheduled dose. Do not take a double dose of this medication.

· If you are taking Thorazine on a regular schedule several times a day, take the missed dose within 1 hour of its regular time. If more than 1 hour has passed, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication.

· If you are taking Thorazine as needed for nausea and vomiting, take the missed dose as soon as possible if needed, then wait at least 4 hours before taking another dose.

 

What happens if I overdose?

· Seek emergency medical attention.

· Symptoms of a Thorazine overdose include uncontrollable movements, agitation, seizures, severe dizziness or fainting, coma, very deep sleep, irregular heartbeats, and high or low body temperature.

 

What should I avoid while taking Thorazine?

· Use caution when driving, operating machinery, or performing other hazardous activities. Thorazine may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities.

· Dizziness may be more likely to occur when you rise from a sitting or lying position. Rise slowly to prevent dizziness and a possible fall.

· Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking Thorazine.

· Avoid prolonged exposure to sunlight. Thorazine may increase the sensitivity of your skin to sunlight. Use a sunscreen and wear protective clothing when sun exposure is unavoidable.

 

What are the possible side effects of Thorazine?

· If you experience any of the following serious side effects, stop taking Thorazine and seek emergency medical treatment:     ·an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);     ·uncontrollable movements of the tongue, face, lips, arms, or legs;     ·muscle spasms of the face or neck;     ·severe restlessness or tremor;     ·severe drowsiness or fainting;     ·a rash; or     ·jaundice (yellowing of the skin or eyes).

· Other, less serious side effects may be more likely to occur. Continue to take Thorazine and talk to your doctor if you experience:     ·decreased sweating;     ·dry mouth or stuffy nose     ·constipation;     ·blurred vision     ·mild restlessness, drowsiness, or tremor;     ·difficult urination or dark urine;     ·decreased sex drive;     ·dizziness;     ·increased appetite; or     ·menstrual irregularities or swollen breasts.

· Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

 

What other drugs will affect Thorazine?

· Before taking this medication, tell your doctor if you are taking any of the following drugs:     ·antacids. Take antacids at least 2 hours before or 2 hours after taking a dose of Thorazine. They will decrease the effectiveness of Thorazine.     ·alcohol; over-the-counter cough, cold, or allergy medications; sleep aids; antidepressants; muscle relaxants; barbiturates; and seizure medications. All of these medications will increase the side of effects of Thorazine-- especially drowsiness and dizziness.     ·blood pressure medications such as propranolol (Inderal), methyldopa (Aldomet), and clonidine (Catapres). These drugs may cause dizziness and fainting if used with Thorazine.     ·anticoagulants such as warfarin (Coumadin). Thorazine may decrease the effectiveness of these medications, and blood clotting could result.     ·phenytoin (Dilantin). Thorazine may increase the effectiveness of phenytoin and cause side effects. You may need smaller doses of phenytoin.

· Drugs other than those listed here may also interact with Thorazine. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

 

Where can I get more information?

· Your pharmacist has additional information about Thorazine written for health professionals that you may read.