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Triavil

Generic Name: amitriptyline and perphenazine
Brands: Etrafon 2-10, Etrafon 2-25, Etrafon Forte


What is the most important information I should know about Triavil?

· Call your doctor immediately if you have uncontrollable movements of your mouth, tongue, cheeks, jaw, arms, or legs.

· Use caution when driving, operating machinery, or performing other hazardous activities. Triavil may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities.

· Dizziness may be more likely to occur when you rise from a sitting or lying position. Rise slowly to prevent dizziness and a possible fall.

· Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking Triavil.

 

What is Triavil?

· Amitriptyline is in a class of drugs called tricyclic antidepressants. It is used to relieve symptoms of depression such as feelings of sadness, worthlessness, or guilt; loss of interest in daily activities; changes in appetite; tiredness; sleeping too much; insomnia; and thoughts of death or suicide. Amitriptyline is also sometimes used to treat certain types of pain.

· Perphenazine is in a class of drugs called phenothiazines. Perphenazine is used to treat psychotic disorders and nausea and vomiting.

· Triavil work by changing the actions of chemicals in your brain.

· The combination, Triavil, is used to treat depression that is accompanied by anxiety or agitation.

· Triavil may also be used for purposes other than those listed in this medication guide.

 

What should I discuss with my healthcare provider before taking Triavil?

· Do not take Triavil if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days, or if you have had a heart attack in the past 6 weeks.

· Before taking Triavil, tell your doctor if you have     ·a bone marrow disease,     ·high blood pressure or any type of heart disease,     ·glaucoma or increased pressure in your eyes,     ·epilepsy or another seizure disorder,     ·Parkinson's disease,     ·liver disease, or     ·an enlarged prostate or difficulty urinating.

· You may not be able to take Triavil, or you may require a lower dose or special monitoring during treatment if you have any of the conditions listed above.

 

· It is not known whether Triavil will harm an unborn baby. Do not take Triavil without first talking to your doctor if you are pregnant.

· It is not known whether Triavil passes into breast milk. Do not take this medication without first talking to your doctor if you are breast-feeding a baby.

 

How should I take Triavil?

· Take Triavil exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

· Take each dose with a full glass of water.

· Do not stop taking Triavil without the approval of your doctor. It may be up to 4 months before you begin to feel better, and you may require continuous treatment for quite some time. Talk to your doctor before you stop taking this medication.

· Store Triavil at room temperature away from moisture and heat.

 

What happens if I miss a dose?

· Take the missed dose as soon as you remember. However, if it is almost time for your next regularly scheduled dose, skip the missed dose and take only the next one as directed. Do not take a double dose of this medication.

 

What happens if I overdose?

· Seek emergency medical treatment.

· Symptoms of an Triavil overdose include hallucinations, confusion, drowsiness, fast heartbeat, large pupils, seizures, low blood pressure (fainting, weakness), vomiting, high or low body temperature, and coma.

 

What should I avoid while taking Triavil?

· Use caution when driving, operating machinery, or performing other hazardous activities. Triavil may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities.

· Dizziness may be more likely to occur when you rise from a sitting or lying position. Rise slowly to prevent dizziness and a possible fall.

· Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking Triavil.

 

What are the possible side effects of Triavil?

· If you experience any of the following serious side effects, stop taking Triavil and seek emergency medical treatment:     ·an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);     ·uncontrollable movements of your tongue, face, lips, arms, or legs;     ·muscle spasms of the face or neck;     ·severe restlessness or tremor;     ·severe drowsiness or fainting; or     ·seizures.

· Other, less serious side effects may be more likely to occur. Continue to take Triavil and talk to your doctor if you experience     ·decreased sweating;     ·dry mouth, stuffy nose;     ·constipation;     ·blurred vision;     ·mild restlessness, drowsiness, or tremor;     ·headache;     ·decreased sex drive;     ·dizziness or unusual weakness;     ·nausea, vomiting, or diarrhea; or     ·menstrual irregularities or swollen breasts.

· Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

 

What other drugs will affect Triavil?

· Do not take Triavil if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days.

· Triavil may increase the effects of other drugs that cause drowsiness, including other antidepressants, alcohol, antihistamines, sedatives (used to treat insomnia), pain relievers, anxiety medicines, and muscle relaxants. Tell your doctor about all medicines that you are taking, and do not take any medicine unless your doctor approves.

· Drugs other than those listed here may also interact with Triavil. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

 

Where can I get more information?

· Your pharmacist has additional information about Triavil written for health professionals that you may read.


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